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Warthin's Tumor

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Let's take a look at this case of an elderly gentleman

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who presented with a palpable mass

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in the right parotid gland.

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On the T2-weighted imaging,

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you see that this lesion has gross heterogeneity

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as far as its signal intensity.

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It almost looks like there's a fluid-fluid level in

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one of the cystic portions of the mass and

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it has some very dark areas as well.

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And it is in the superficial portion of the parotid

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gland. And if we take the images a little bit lower,

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you can see that it gets down to the angle of the

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mandible here. So a large lesion, heterogeneous.

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This is not what we would expect of

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a pleomorphic adenoma, not at all.

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On the T1-weighted scan we see both the brighter

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areas as well as the darker areas.

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Again, having something that has bright areas within the

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mass is not typical of a pleomorphic adenoma.

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That's more likely to be something like a Warthin's

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tumour with its heterogeneity. Now,

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we want to make sure that this wasn't biopsied,

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but the next thing we look at is the ADC map.

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So if it's bright on the ADC map,

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we'll feel a little bit more reassured

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that this is a benign tumour,

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possibly one of those monomorphic adenomas or

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something atypical about a pleomorphic adenoma.

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However, this is the ADC map and as you can see,

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we have dark areas,

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very dark area, more posteriorly in this mass.

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There might be a little bit of a cystic

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component out superficially,

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but this is not a reassuring finding.

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So now we have a high likelihood that

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this is a Warthin's tumour.

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Based on the heterogeneity on T1 as well as T2

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and the lower signal intensity on the ADC map,

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this would still require aspiration cytology

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in order to exclude a malignancy.

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If that aspiration cytology is equivocal,

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what one can try is a technetium pertechnetate

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nuclear medicine study.

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Warthin's tumours are relatively unique in that they

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show avid uptake of technetium pertechnetate as

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opposed to pleomorphic adenomas and most malignancies.

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So that would be our next step.

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Just for the sake of completion,

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we will look at this on post-gadolinium enhanced scan

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and Warthin's tumors do show enhancement.

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You can see that there are portions that are and are

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not enhancing in this lesion as

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well as this cystic area,

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which may occur both in malignancies as well

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as pleomorphic adenomas. At this juncture,

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one of the next things you want to do is to make sure

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you look through the contralateral parotid gland and

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elsewhere within the ipsilateral parotid and to

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ensure that there are not multiple lesions.

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As Warthin's Tumor is the most common tumor

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to have bilateral and or multiple ipsilateral tumors.

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There's something over here which kind of looks

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more like a lymph node than anything else.

Report

Description

Faculty

David M Yousem, MD, MBA

Professor of Radiology, Vice Chairman and Associate Dean

Johns Hopkins University

Tags

Salivary Glands

Neuroradiology

Neoplastic

MRI

Head and Neck

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