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Proptosis from Extraosseous Extension of Prostate Metastasis

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This was the case of a gentleman who complained of

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sinus congestion as well as bilateral proptosis.

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The axial scans, as we scroll through the brain, show

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complete opacification of the ethmoid sinuses.

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And we note that the patient has had previous surgery on

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the maxillary antrum with medial antrostomies, and there is

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mucosal thickening bilaterally in the maxillary

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antrum at the superior portion of the orbit.

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We notice that there is an abnormality which

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is seen medial to the medial rectus muscle.

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The muscle is seen displaced inward, and when we think

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of all comers, we might suggest that this could be an

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infectious etiology secondary to the ethmoid sinusitis.

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But let's look at the case a little bit

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more carefully on the coronal images.

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On the coronal images, we note that this collection is

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actually far superior in the orbit, in the superior medial

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aspect of the orbit and not directly

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adjacent to the ethmoid sinus.

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The abnormality is low in density and it's seen between

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the superior rectus muscle and the inferior rectus muscle.

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Not only that,

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but it seems to extend into the orbital roof along the

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expected location of the Levator palpebrae muscle.

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Looking at the bone windows,

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we note that there is thickening of the bone in the

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orbital roof and that in point of fact there is diffuse

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abnormality in the density of the skull base.

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The pterygoid bones,

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as well as the walls of the sphenoid, are abnormal.

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If we allow our eyes to stray down to the mandibles, we

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also see that there is bony reaction along the mandible

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with abnormal density not only in the mandible,

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but along the pterygoid bones and even along portions of

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the temporal bone and the anterior clinoid process.

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This patient has diffuse metastatic disease to the bone

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from prostate cancer, and this extraconal abnormality is

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actually extraosseous tumoral infiltration of the orbit

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by the bone metastases, rather than a manifestation of the

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perinasal sinusitis. So that sinusitis was coincidental,

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but the abnormality was diffuse metastatic disease to bone

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with extraosseous extension into

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the extraconal space.

Report

Description

Faculty

David M Yousem, MD, MBA

Professor of Radiology, Vice Chairman and Associate Dean

Johns Hopkins University

Tags

Skull Base

Orbit

Neuroradiology

Neuro

Neoplastic

Musculoskeletal (MSK)

Head and Neck

CT

Bone & Soft Tissues

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