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Choledocholithiasis

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0:01

So this patient is a 60-year-old

0:02

female, and the history provided

0:04

is elevated liver function tests.

0:07

LFTs are elevated.

0:09

Um, wanted to get an MRI; sounds very reasonable.

0:12

So we do our MRI examination, and we're going

0:14

to go through some sequences to see if we

0:16

can figure out what's causing these problems.

0:19

So here's our T2-weighted sequence,

0:20

non-fat-saturated in the axial plane.

0:24

And we see what probably amounts

0:25

to a small liver cyst over there.

0:27

We can ignore that for the moment.

0:29

And as we go down, we already start to

0:32

see that the bile ducts are dilated.

0:35

Now remember, if you've gone through

0:37

sort of the normal anatomy on these T2

0:39

weighted sequences, you hardly ever get

0:42

to see the intrahepatic bile ducts.

0:43

They're so small, they should

0:44

be less than two millimeters.

0:46

So the fact that I'm seeing the bile

0:48

ducts on my T2-weighted sequences

0:50

here tells me that they’re dilated.

0:53

Doesn't necessarily have to mean there’s

0:54

some abnormality associated with it,

0:56

but it does mean that they are dilated.

0:59

So let’s figure out if we

1:00

can see why they’re dilated.

1:02

You can see here, very, very dilated.

1:05

And again, this is the extrahepatic biliary tree.

1:07

You can see the cystic duct

1:08

over here on this image.

1:09

We start to see a bit of a gallbladder.

1:11

You can see some gallstones here,

1:13

T2 hypointense filling defects.

1:15

But let's ignore that again for the moment.

1:16

Let's focus right over here on

1:19

the extrahepatic biliary tree.

1:22

And already, the next slice downwards, you

1:24

can start to see a filling defect inside

1:27

the common hepatic duct over here.

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At this point, it may even

1:29

be the common bile duct.

1:31

Certainly, as you go lower, it starts

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to become the common bile duct.

1:33

Another filling defect here, another filling

1:35

defect here, T2 hypointense, and quite a

1:38

large one here within the common bile duct.

1:42

Another one here.

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And we can go all the way downwards

1:45

and see that it looks relatively clean.

1:49

Let's look at the same findings, but just

1:50

on a different plane, the coronal plane.

1:53

Again, we can see that the

1:54

intrahepatic tree is dilated.

1:56

Both the right and left hepatic ducts,

1:57

the common hepatic duct is dilated.

2:00

As we go downwards, we can start to

2:02

see that there are numerous filling

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defects inside the common bile duct.

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Various shapes, various sizes, all of them

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are T2 hypointense as we go downwards.

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And so these are going to be

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some filling defects here.

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We can look at the same thing on

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our T2 fat-saturated sequences.

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A little bit more motion here, but we can

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certainly appreciate the filling defects.

2:20

And notice how all these filling

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defects are dependent.

2:23

Right.

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So they're sort of going to the dependent

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portion over here, which is obviously posteriorly

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and they're lying down upon the dependent

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portion of the bile duct for the most part.

2:34

We can look at the same thing

2:36

on our T1 pre-contrast image.

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And we notice that some of these

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filling defects, a lot of

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them really are T1 hyperintense.

2:46

And in this instance, we did an MRCP.

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And so I just want to finish off the

2:50

description by showing you the MRCP images,

2:52

and the images came out reasonably well.

2:57

You can see that the intrahepatic bile ducts are

2:59

dilated; the extrahepatic biliary tree is dilated.

3:01

You can start to see some filling

3:04

defects inside the extrahepatic biliary tree.

3:06

And this is sort of an MIP image showing

3:08

at least one of those filling defects.

3:09

And so again, you know, this is not giving

3:11

me any extra information that I haven't

3:13

gleaned from my other sequences, but, you

3:15

know, nevertheless, this may be useful.

3:17

And so what's going on here?

3:19

You may have guessed it already.

3:20

This is an example of choledocholithiasis.

3:23

Choledocholithiasis refers to the

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presence of stones in the bile ducts.

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Oftentimes, we see it due to the passage of stones

3:32

from the gallbladder that escape and go into

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the extrahepatic biliary tree, but it's

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important to know that they can potentially

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form in the absence of gallstones in the

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setting of biliary stasis for whatever reason.

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Oftentimes, patients may present with

3:47

biliary colic as a result of these stones.

3:51

We also see patients who are relatively

3:52

asymptomatic and just sort of present with

3:55

incidentally noted choledocholithiasis.

3:58

Most times, if patients are suspecting

4:00

choledocholithiasis, they will get an ultrasound,

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but oftentimes, the more distal aspects of the

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common bile duct are tough to see on ultrasound.

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And so an MRI is pretty rare

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often performed if the findings

4:12

are unclear on ultrasound.

4:13

Choledocholithiasis essentially

4:16

looks very similar to this.

4:17

They're dependent filling defects,

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with relatively geographic shapes, such as

4:20

circles or small triangles.

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All of them will be T2 hypointense.

4:25

Most times they're also T1 hypointense.

4:28

In this case, these were T1 hyperintense,

4:31

which you could see with pigmented stones.

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It's also important to understand that

4:36

MRI is very good at detecting these, but

4:38

occasionally, if they are very tiny stones,

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maybe two millimeters or even three millimeters

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or less, we may end up missing those stones.

4:46

So sometimes we'll call it no choledocholithiasis

4:49

and then an ERCP may reveal

4:51

a few tiny stones that were missed.

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But MRI does fairly well for the most part

4:56

in detecting choledocholithiasis, and this is a

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nice case of choledocholithiasis resulting in

5:01

biliary ductal dilatation and presumably the

5:03

elevated liver function tests in this patient.

Report

Faculty

Mahan Mathur, MD

Associate Professor, Division of Body Imaging; Vice Chair of Education, Dept of Radiology and Biomedical Imaging

Yale School of Medicine

Tags

Syndromes

Other Biliary

Non-infectious Inflammatory

Metabolic

MRI

Liver

Idiopathic

Gastrointestinal (GI)

Gallbladder

CT

Body

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