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Osteomyelitis

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0:01

Here we have a child who presented

0:03

with left hip pain, uh, and fever.

0:07

So I have three images here

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for you, or three sequences.

0:10

The image on the left is a

0:13

coronal T1 fat sat post-contrast.

0:16

That image in the middle is actually the same.

0:18

Let me bring up this one, which is an STIR.

0:20

Let me zoom up a little.

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So this STIR is a fat-suppressed fluid

0:23

sensitive sequence, which demonstrates

0:25

again in the area of abnormal

0:27

enhancement, there is a lot of edema.

0:29

So this extends to the acetabular tectum.

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Not really a lot of joint effusion

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associated, and it sort of stops in

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the region of the triradiate cartilage.

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Here are the axial post-contrast images.

0:41

Going through the similar area shows

0:43

that, indeed, there is quite a bit of

0:45

enhancement, and even a little bit of

0:47

periosteal reaction here at the periphery.

0:50

You have the normal side on the right for

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comparison, showing that, really, there

0:53

should be nothing here at the periphery.

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Inflammation happening here.

0:57

So, the first thought when you

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see this, especially with that

1:00

history, should be infection.

1:03

Indeed, this is what this ended up

1:04

being; this ended up being osteomyelitis.

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And the reason I'm showing this case is

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because it proves, or it suggests, one of

1:11

the key teaching points in the pediatric

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population is that stuff around cartilaginous

1:16

margins, such as the triradiate cartilage,

1:19

should be treated as a metaphyseal equivalent.

1:21

So this area really is a metaphyseal equivalent.

1:24

And why is that important?

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It's because the metaphysis is

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a very richly vascular area.

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There's an area where the flow is very, very

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slow, and if there is an infection that's

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hematogenously being spread, the metaphysis

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is a great location for it, and because

1:41

this portion of the pelvic bone is a

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metaphyseal equivalent, this is also a

1:46

great place for infection to embed itself.

1:49

So, I want to leave you with one other thought.

1:53

Anytime I see inflammation in the pelvic

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area, around the sacroiliac joints, around

2:00

the pelvis, I also think of another diagnosis,

2:03

which is coming up more and more now, and

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that's called chronic recurrent multifocal

2:07

osteomyelitis, or CRMO.

2:13

The name says osteomyelitis, but it

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really isn't a bacterial infection per se.

2:19

It's more of a chronic,

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uh, inflammatory process.

2:22

Some people think it's

2:23

autoimmune, not really sure.

2:25

But when I see a lesion like this, I say,

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probably osteomyelitis, but in the back of

2:30

your mind, consider, could this be CRMO?

2:33

If you think it's CRMO,

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look for other lesions.

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Oftentimes, these CRMO lesions will

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have lesions in the contralateral side,

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uh, around the sacroiliac joints, around

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the hips, and in the vertebral bodies.

2:47

But just because you don't see

2:48

it doesn't mean it's not true.

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If CRMO is suspected,

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oftentimes you'll need to get a whole

2:54

body MRI to look for other lesions.

2:56

And the treatment is completely

2:58

different for those two entities.

3:00

Oftentimes, CRMO needs a biopsy to

3:02

diagnose. Infection may

3:06

need a biopsy also if it's not being, if

3:08

it's not being treated well or it's not

3:10

responding properly to antibiotic therapy.

3:13

But this ended up being osteomyelitis,

3:15

but it easily could have been a

3:17

condition called CRMO.

Report

Faculty

Mahesh Thapa, MD, MEd, FAAP

Division Chief of Musculoskeletal Imaging, and Director of Diagnostic Imaging Professor

Seattle Children's & University of Washington

Tags

Pediatrics

Musculoskeletal (MSK)

MRI

Infectious

Idiopathic

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