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Pre-ossification Centers

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Before we get to our next case, I want

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to briefly illustrate for you a point I

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mentioned in one of the earlier vignettes.

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I mentioned that the epiphysis has

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blood vessels that run through it, okay?

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So what does that mean as far as the

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development of the epiphyseal cartilage?

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So let's draw that epiphyseal

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cartilage one more time.

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Nice big cartilaginous epiphysis, okay?

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Within this, we have coalescence

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of blood vessels in their own

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channels at various locations.

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That's just for the sake of argument.

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Let's take that.

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Okay, the blood vessels

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are running through this.

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These blood vessels are not just blood vessels.

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There are arterioles, venules,

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lymphatics, connective tissue, all

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bringing nutrients into the cartilage

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and taking waste products away.

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That's the function.

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Okay.

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One of the things that it brings in is

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mineralization factors and apoptotic

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factors, just like we saw in the metaphysis.

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So, what does that do?

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That readies the cartilaginous

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portion to undergo ossification.

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It tells it to become bone, okay?

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So when that happens, there's the forming of

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what's called a preossification center, okay?

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That preossification center

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happens around blood vessels.

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And that preossification center is

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going to look something like this.

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And it's going to be very bright.

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Because it's going to be fluid-rich.

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It's going to be cartilage cell-rich.

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That's very big cartilage cells

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that have a lot of fluid in them.

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Okay.

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And it's going to look like a blister in

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the cartilaginous center of the cartilage.

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You don't see it all the time.

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But it typically happens around

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the knee, the femoral condyles.

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It typically happens around the elbow,

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around the trochlea of the elbow,

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and that's what I want to show you.

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This is a normal finding and it's

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important not to call it cartilage

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injury or an area of cartilage damage.

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So now let's go on and take a look

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at a case that represents this.

Report

Faculty

Mahesh Thapa, MD, MEd, FAAP

Division Chief of Musculoskeletal Imaging, and Director of Diagnostic Imaging Professor

Seattle Children's & University of Washington

Tags

Pediatrics

Musculoskeletal (MSK)

MRI

Acquired/Developmental

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