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Legg-Calvé-Perthes disease on MRI

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On the previous vignette, I showed you this

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six-year-old patient's radiograph, which

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demonstrated some collapse and sclerosis

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of the right femoral head, a little bit

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of lucency under the subchondral surface,

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and what looked like a joint effusion.

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This is the MR, and I think we can

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see many of those findings here.

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We have a coronal, fat-suppressed,

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fluid-sensitive sequence.

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All this bright stuff in the joint is

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fluid, and look how asymmetric it is

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compared to the contralateral normal side.

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So indeed, there was joint effusion, as

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manifested by displacement of some of the soft

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tissue structures on the plain radiograph.

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That area of subchondral lucency is seen very

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well as an area of high signal, serpiginous, just

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under the chondral surface on the right side.

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And the fact that the head is a little

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flattened up here, compared to the

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contralateral side, tells me that there is

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a little bit of collapse that has happened.

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So these are all signs of decreased perfusion,

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or not getting enough blood supply, avascular

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necrosis, however you want to call it.

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In addition, what this shows that the plain

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film doesn't show is that some of these

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changes are also happening in the metaphysis.

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Look how the metaphysis is brighter.

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On the lateral side and also on the

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medial side, showing that there is some

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added stress happening causing edema,

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and inflammation in this area, okay?

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And there's also some areas or some

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pockets of increased fluid-like signal

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in the capital femoral epiphysis.

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I want to show you the value of

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contrast imaging on a patient like this.

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So I'm going to bring up three images at once.

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So on this one, I'm going to put the

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coronal T1 Fatsat, which is this.

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In the middle image, I'm going to

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put coronal T1 Fatsat post-contrast.

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And on the final, I'm going to put a

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coronal T1 Fatsat subtracted image.

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In fact, I'm going to go just like this,

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so you can see as much of this as possible.

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And really, you want to look

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at both sides at the same time.

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Again, this is fat-saturated without

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contrast, and this is fat-saturated

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T1 with IV contrast in place.

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And this here is a fat-saturated subtracted image.

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In other words, I took this image

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and digitally subtracted out this

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image to give you this image.

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So, pre-contrast, we sort of

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see the areas of effusion.

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We see a little bit of collapse.

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You know, we see the area of abnormal

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signal here that was shown as bright

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signal on the STIR on the lateral aspect.

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After we give contrast, we notice that there

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is considerable enhancement of the synovium.

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There is enhancement in the area of edema.

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There is enhancement in the area in the

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periphery here, both laterally and medially, but

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no significant enhancement in the femoral head.

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Compare it to the normal left side.

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There should still be some minimal

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enhancement on a normal ossified femoral

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capital epiphysis, as we see over here.

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The reason we get the subtracted image is if

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there are subtle findings of decreased enhancement

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on one versus the other, it becomes magnified.

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It becomes really much more

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conspicuous than the subtracted images.

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Look at this image and this image.

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Yes, you can tell there's a difference

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between this and this, but look how dramatic

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that difference is in the subtracted images.

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So if you do post-contrast images looking

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for avascular necrosis, it really behooves

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you to get subtracted images, because if

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there are subtle changes, maybe not as

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dramatic as this, you will pick it up on

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the subtracted images, where you may not

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pick it up on the non-subtracted images.

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Again, we see beautifully the areas of

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contrast enhancement, in the synovium, in

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the metaphysis, and at the periphery of the

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epiphysis, with a central area of non-enhancement.

Report

Faculty

Mahesh Thapa, MD, MEd, FAAP

Division Chief of Musculoskeletal Imaging, and Director of Diagnostic Imaging Professor

Seattle Children's & University of Washington

Tags

Pediatrics

Non-infectious Inflammatory

Musculoskeletal (MSK)

MRI

Idiopathic

Acquired/Developmental

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